CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription

Retroviruses pack multiple genes into relatively small genomes by encoding several genes in the same genomic region with overlapping reading frames. Both sense and antisense HIV-1 transcripts contain open reading frames for known functional proteins as well as numerous alternative reading frames (AR...

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Hlavní autoři: Bansal, Anju, Carlson, Jonathan, Yan, Jiyu, Akinsiku, Olusimidele T., Schaefer, Malinda, Sabbaj, Steffanie, Bet, Anne, Levy, David N., Heath, Sonya, Tang, Jianming, Kaslow, Richard A., Walker, Bruce D., Ndung’u, Thumbi, Goulder, Philip J., Heckerman, David, Hunter, Eric, Goepfert, Paul A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812545/
https://ncbi.nlm.nih.gov/pubmed/20065064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092060
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