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Inhibition of deoxyribonucleases by phosphorothioate groups in oligodeoxyribonucleotides.
The Rp- and Sp-diastereomers of the phosphorothioate-containing oligonucleotide d[ApAp(S)ApA] have been synthesized. They and the tetramer d[ApApApA] were tested as substrates for staphylococcal nuclease, DNase II and spleen phosphodiesterase. For digestions with DNase I these oligonucleotides were...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1988
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC339104/ https://ncbi.nlm.nih.gov/pubmed/2850541 |
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