Caloric Restriction Extends Yeast Chronological Lifespan by Altering a Pattern of Age-Related Changes in Trehalose Concentration

The non-reducing disaccharide trehalose has been long considered only as a reserve carbohydrate. However, recent studies in yeast suggested that this osmolyte can protect cells and cellular proteins from oxidative damage elicited by exogenously added reactive oxygen species (ROS). Trehalose has been...

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Autors principals: Kyryakov, Pavlo, Beach, Adam, Richard, Vincent R., Burstein, Michelle T., Leonov, Anna, Levy, Sean, Titorenko, Vladimir I.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390693/
https://ncbi.nlm.nih.gov/pubmed/22783207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00256
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