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Reduced Alpha-Lipoic Acid Synthase Gene Expression Exacerbates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice
OBJECTIVES: To study the effects of reduced lipoic acid gene expression on diabetic atherosclerosis in apolipoprotein E null mice (Apoe(−)(/)(−)). METHODS AND RESULTS: Heterozygous lipoic acid synthase gene knockout mice (Lias(+/)(−)) crossed with Apoe(−)(/)(−) mice were used to evaluate the diabeti...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389304/ https://ncbi.nlm.nih.gov/pubmed/22658261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.04.025 |
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