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Comparative enzymology of (2S,4R)4-fluoroglutamine and (2S,4R)4-fluoroglutamate

Many cancer cells have a strong requirement for glutamine. As an aid for understanding this phenomenon the (18)F-labeled 2S,4R stereoisomer of 4-fluoroglutamine [(2S,4R)4-FGln] was previously developed for in vivo positron emission tomography (PET). In the present work, comparative enzymological stu...

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Detalhes bibliográficos
Main Authors: Cooper, Arthur J. L., Krasnikov, Boris F., Pinto, John T., Kung, Hank F., Li, Jianyong, Ploessl, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389287/
https://ncbi.nlm.nih.gov/pubmed/22613816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpb.2012.05.010
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