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A polymorphism in the upstream regulatory region of the interleukin-1α gene confers differential binding by transcription factors of the AP-1 family
AIMS: Previous genetic studies have shown that a C/T polymorphism at position −889 of the IL1A promoter, specifically allele 2 (−889T), increases the risk for development of several inflammation-related disorders, such as periodontitis, osteomyelitis, toxoplasmic retinochoroiditis, contact dermatiti...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389230/ https://ncbi.nlm.nih.gov/pubmed/22634325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.05.004 |
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