Potential Autoregulation of Transcription Factor PU.1 by an Upstream Regulatory Element

Regulation of the hematopoietic transcription factor PU.1 (Spi-1) plays a critical role in the development of white cells, and abnormal expression of PU.1 can lead to leukemia. We previously reported that the PU.1 promoter cannot induce expression of a reporter gene in vivo, and cell-type-specific e...

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Detalhes bibliográficos
Main Authors: Okuno, Yutaka, Huang, Gang, Rosenbauer, Frank, Evans, Erica K., Radomska, Hanna S., Iwasaki, Hiromi, Akashi, Koichi, Moreau-Gachelin, Francoise, Li, Youlin, Zhang, Pu, Göttgens, Berthold, Tenen, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061634/
https://ncbi.nlm.nih.gov/pubmed/15767686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.7.2832-2845.2005
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