Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation

The PU.1 transcription factor is a key regulator of hematopoietic development, but its role at each hematopoietic stage remains unclear. In particular, the expression of PU.1 in hematopoietic stem cells (HSCs) could simply represent “priming” of genes related to downstream myelolymphoid lineages. By...

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Detalhes bibliográficos
Main Authors: Iwasaki, Hiromi, Somoza, Chamorro, Shigematsu, Hirokazu, Duprez, Estelle A., Iwasaki-Arai, Junko, Mizuno, Shin-ichi, Arinobu, Yojiro, Geary, Kristin, Zhang, Pu, Dayaram, Tajhal, Fenyus, Maris L., Elf, Shannon, Chan, Susan, Kastner, Philippe, Huettner, Claudia S., Murray, Richard, Tenen, Daniel G., Akashi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Hematopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895212/
https://ncbi.nlm.nih.gov/pubmed/15914556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-0860
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