Respiratory Failure Due to Differentiation Arrest and Expansion of Alveolar Cells following Lung-Specific Loss of the Transcription Factor C/EBPα in Mice

The leucine zipper family transcription factor CCAAT enhancer binding protein alpha (C/EBPα) inhibits proliferation and promotes differentiation in various cell types. In this study, we show, using a lung-specific conditional mouse model of C/EBPα deletion, that loss of C/EBPα in the respiratory epi...

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Main Authors: Bassères, Daniela S., Levantini, Elena, Ji, Hongbin, Monti, Stefano, Elf, Shannon, Dayaram, Tajhal, Fenyus, Maris, Kocher, Olivier, Golub, Todd, Wong, Kwok-kin, Halmos, Balazs, Tenen, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347037/
https://ncbi.nlm.nih.gov/pubmed/16428462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.1109-1123.2006
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