Acetaminophen Inhibits Cytochrome C Redox Cycling Induced Lipid Peroxidation

Cytochrome (cyt) c can uncouple from the respiratory chain following mitochondrial stress and catalyze lipid peroxidation. Accumulating evidence shows that this phenomenon impairs mitochondrial respiratory function and also initiates the apoptotic cascade. Therefore, under certain conditions a pharm...

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Detalhes bibliográficos
Main Authors: Yin, Huiyong, Vergeade, Aurélia, Shi, Qiong, Zackert, William E., Gruenberg, Katherine C., Bokiej, Magdalena, Amin, Taneem, Ying, Weizhen, Masterson, Tina S., Zinkel, Sandra S., Oates, John A., Boutaud, Olivier, Roberts, L. Jackson
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389218/
https://ncbi.nlm.nih.gov/pubmed/22634010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.05.058
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