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Degrees of chloroquine resistance in Plasmodium – Is the redox system involved?

Chloroquine (CQ) was once a very effective antimalarial drug that, at its peak, was consumed in the hundreds of millions of doses per year. The drug acts against the Plasmodium parasite during the asexual intra-erythrocytic phase of its lifecycle. Unfortunately, clinical resistance to this drug is n...

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Detalhes bibliográficos
Main Authors: Lehane, Adele M., McDevitt, Christopher A., Kirk, Kiaran, Fidock, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388501/
https://ncbi.nlm.nih.gov/pubmed/22773965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2011.11.001
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