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Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase

Non-reproducible sequence artefacts are frequently detected in DNA from formalin-fixed and paraffin-embedded (FFPE) tissues. However, no rational strategy has been developed for reduction of sequence artefacts from FFPE DNA as the underlying causes of the artefacts are poorly understood. As cytosine...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Do, Hongdo, Dobrovic, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388184/
https://ncbi.nlm.nih.gov/pubmed/22643842
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