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Isolation and next generation sequencing of archival formalin‐fixed DNA

DNA from archived organs is presumed unsuitable for genomic studies because of excessive formalin‐fixation. As next generation sequencing (NGS) requires short DNA fragments, and Uracil‐N‐glycosylase (UNG) can be used to overcome deamination, there has been renewed interest in the possibility of geno...

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Dades bibliogràfiques
Publicat a:J Anat
Autors principals: Alqahtani, Ahlam, Skelton, Andrew, Eley, Lorraine, Annavarapu, Srinivas, Henderson, Deborah J., Chaudhry, Bill
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476199/
https://ncbi.nlm.nih.gov/pubmed/32426881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.13209
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