Isolation and next generation sequencing of archival formalin‐fixed DNA

DNA from archived organs is presumed unsuitable for genomic studies because of excessive formalin‐fixation. As next generation sequencing (NGS) requires short DNA fragments, and Uracil‐N‐glycosylase (UNG) can be used to overcome deamination, there has been renewed interest in the possibility of geno...

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Bibliographic Details
Published in:J Anat
Main Authors: Alqahtani, Ahlam, Skelton, Andrew, Eley, Lorraine, Annavarapu, Srinivas, Henderson, Deborah J., Chaudhry, Bill
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
Subjects:
Methods
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476199/
https://ncbi.nlm.nih.gov/pubmed/32426881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.13209
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