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Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase

Non-reproducible sequence artefacts are frequently detected in DNA from formalin-fixed and paraffin-embedded (FFPE) tissues. However, no rational strategy has been developed for reduction of sequence artefacts from FFPE DNA as the underlying causes of the artefacts are poorly understood. As cytosine...

詳細記述

保存先:
書誌詳細
主要な著者: Do, Hongdo, Dobrovic, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388184/
https://ncbi.nlm.nih.gov/pubmed/22643842
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