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High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies

BACKGROUND: Epithelial growth factor receptor (EGFR) and KRAS mutation status have been reported as predictive markers of tumour response to EGFR inhibitors. High resolution melting (HRM) analysis is an attractive screening method for the detection of both known and unknown mutations as it is rapid...

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Detalhes bibliográficos
Main Authors: Do, Hongdo, Krypuy, Michael, Mitchell, Paul L, Fox, Stephen B, Dobrovic, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408599/
https://ncbi.nlm.nih.gov/pubmed/18495026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-142
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