KRAS Mutation Detection in Paired Frozen and Formalin-Fixed Paraffin-Embedded (FFPE) Colorectal Cancer Tissues

KRAS mutation has been unambiguously identified as a marker of resistance to cetuximab-based treatment in metastatic colorectal cancer (mCRC) patients. However, most studies of KRAS mutation analysis have been performed using homogenously archived CRC specimens, and studies that compare freshly froz...

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Autors principals: Solassol, Jérome, Ramos, Jeanne, Crapez, Evelyne, Saifi, Majda, Mangé, Alain, Vianès, Evelyne, Lamy, Pierre-Jean, Costes, Valérie, Maudelonde, Thierry
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116185/
https://ncbi.nlm.nih.gov/pubmed/21686179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12053191
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