Phenotype Selection Reveals Coevolution of Muscle Glycogen and Protein and PTEN as a Gate Keeper for the Accretion of Muscle Mass in Adult Female Mice

We have investigated molecular mechanisms for muscle mass accretion in a non-inbred mouse model (DU6P mice) characterized by extreme muscle mass. This extreme muscle mass was developed during 138 generations of phenotype selection for high protein content. Due to the repeated trait selection a compl...

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Main Authors: Sawitzky, Mandy, Zeissler, Anja, Langhammer, Martina, Bielohuby, Maximilian, Stock, Peggy, Hammon, Harald M., Görs, Solvig, Metges, Cornelia C., Stoehr, Barbara J. M., Bidlingmaier, Martin, Fromm-Dornieden, Carolin, Baumgartner, Bernhard G., Christ, Bruno, Brenig, Bertram, Binder, Gerhard, Metzger, Friedrich, Renne, Ulla, Hoeflich, Andreas
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387210/
https://ncbi.nlm.nih.gov/pubmed/22768110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039711
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