Phenotype Selection Reveals Coevolution of Muscle Glycogen and Protein and PTEN as a Gate Keeper for the Accretion of Muscle Mass in Adult Female Mice

We have investigated molecular mechanisms for muscle mass accretion in a non-inbred mouse model (DU6P mice) characterized by extreme muscle mass. This extreme muscle mass was developed during 138 generations of phenotype selection for high protein content. Due to the repeated trait selection a compl...

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Main Authors: Sawitzky, Mandy, Zeissler, Anja, Langhammer, Martina, Bielohuby, Maximilian, Stock, Peggy, Hammon, Harald M., Görs, Solvig, Metges, Cornelia C., Stoehr, Barbara J. M., Bidlingmaier, Martin, Fromm-Dornieden, Carolin, Baumgartner, Bernhard G., Christ, Bruno, Brenig, Bertram, Binder, Gerhard, Metzger, Friedrich, Renne, Ulla, Hoeflich, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387210/
https://ncbi.nlm.nih.gov/pubmed/22768110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039711
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