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Lifelong Obesity in a Polygenic Mouse Model Prevents Age- and Diet-Induced Glucose Intolerance– Obesity Is No Road to Late-Onset Diabetes in Mice

AIMS/HYPOTHESIS: Visceral obesity holds a central position in the concept of the metabolic syndrome characterized by glucose intolerance in humans. However, until now it is unclear if obesity by itself is responsible for the development of glucose intolerance. METHODS: We have used a novel polygenic...

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Detalhes bibliográficos
Main Authors: Renne, Ulla, Langhammer, Martina, Brenmoehl, Julia, Walz, Christina, Zeissler, Anja, Tuchscherer, Armin, Piechotta, Marion, Wiesner, Rudolf J., Bielohuby, Maximilian, Hoeflich, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827443/
https://ncbi.nlm.nih.gov/pubmed/24236159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079788
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