Phosphorylation of Kif26b Promotes Its Polyubiquitination and Subsequent Proteasomal Degradation during Kidney Development

Kif26b, a member of the kinesin superfamily proteins (KIFs), is essential for kidney development. Kif26b expression is restricted to the metanephric mesenchyme, and its transcription is regulated by a zinc finger transcriptional regulator Sall1. However, the mechanism(s) by which Kif26b protein is r...

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Main Authors: Terabayashi, Takeshi, Sakaguchi, Masaji, Shinmyozu, Kaori, Ohshima, Toshio, Johjima, Ai, Ogura, Teru, Miki, Hiroaki, Nishinakamura, Ryuichi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387196/
https://ncbi.nlm.nih.gov/pubmed/22768111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039714
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