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Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1
Egr-1 is an inducible transcription factor that recognizes 9-bp target DNA sites via three zinc finger domains and activates genes in response to cellular stimuli such as synaptic signals and vascular stresses. Using spectroscopic and computational approaches, we have studied structural, dynamic, an...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387110/ https://ncbi.nlm.nih.gov/pubmed/22675124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121500109 |
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