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Mechanistic basis for low threshold mechanosensitivity in voltage-dependent K(+) channels

Living cells respond to mechanical forces applied to their outer membrane through processes referred to as “mechanosensation”. Faced with hypotonic shock, to circumvent cell lysis, bacteria open large solute-passing channels to reduce the osmotic pressure gradient. In the vascular beds of vertebrate...

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Bibliographic Details
Main Authors: Schmidt, Daniel, del Mármol, Josefina, MacKinnon, Roderick
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387069/
https://ncbi.nlm.nih.gov/pubmed/22675122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204700109
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