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Studies on the t-butyldimethylsilyl group as 2'-O-protection in oligoribonucleotide synthesis via the H-phosphonate approach.

Two model compounds, 1 and 2, have been studied to test the stability of the t-butyldimethylsilyl (t-BDMSi) group towards conditions used during chemical synthesis of RNA fragments by the H-phosphonate approach. When 1 was treated with anhydrous acid for 16 h both the H-phosphonate diester and the t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Stawinski, J, Strömberg, R, Thelin, M, Westman, E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 1988
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174451/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.19.9285
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