Oxidative stress fuels Trypanosoma cruzi infection in mice

Oxidative damage contributes to microbe elimination during macrophage respiratory burst. Nuclear factor, erythroid-derived 2, like 2 (NRF2) orchestrates antioxidant defenses, including the expression of heme-oxygenase–1 (HO-1). Unexpectedly, the activation of NRF2 and HO-1 reduces infection by a num...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Paiva, Claudia N., Feijó, Daniel F., Dutra, Fabianno F., Carneiro, Vitor C., Freitas, Guilherme B., Alves, Letícia S., Mesquita, Jacilene, Fortes, Guilherme B., Figueiredo, Rodrigo T., Souza, Heitor S.P., Fantappié, Marcelo R., Lannes-Vieira, Joseli, Bozza, Marcelo T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386808/
https://ncbi.nlm.nih.gov/pubmed/22728935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58525
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