Oxidative stress fuels Trypanosoma cruzi infection in mice

Oxidative damage contributes to microbe elimination during macrophage respiratory burst. Nuclear factor, erythroid-derived 2, like 2 (NRF2) orchestrates antioxidant defenses, including the expression of heme-oxygenase–1 (HO-1). Unexpectedly, the activation of NRF2 and HO-1 reduces infection by a num...

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Bibliografische gegevens
Hoofdauteurs: Paiva, Claudia N., Feijó, Daniel F., Dutra, Fabianno F., Carneiro, Vitor C., Freitas, Guilherme B., Alves, Letícia S., Mesquita, Jacilene, Fortes, Guilherme B., Figueiredo, Rodrigo T., Souza, Heitor S.P., Fantappié, Marcelo R., Lannes-Vieira, Joseli, Bozza, Marcelo T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386808/
https://ncbi.nlm.nih.gov/pubmed/22728935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58525
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