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Perforin-expressing cytotoxic cells contribute to chronic cardiomyopathy in Trypanosoma cruzi infection

Understanding the dual participation of the immune response in controlling the invader and at the same time causing tissue damage might contribute to the design of effective new vaccines and therapies for Chagas disease. Perforin, a cytolytic protein product of killer cells, is involved in resistanc...

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Autores principales: Silverio, Jaline Coutinho, de-Oliveira-Pinto, Luzia Maria, da Silva, Andréa Alice, de Oliveira, Gabriel Melo, Lannes-Vieira, Joseli
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812730/
https://ncbi.nlm.nih.gov/pubmed/19878357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2009.00670.x
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