Cytotoxicity of 3-(3,5-Dichlorophenyl)-2,4-thiazolidinedione (DCPT) and Analogues in Wild Type and CYP3A4 Stably Transfected HepG2 Cells

The thiazolidinedione (TZD) ring is a constituent of the glitazones that are used to treat type II diabetes. Liver injury has been reported following chronic glitazone use; however, they do not produce hepatic damage in common laboratory animal species. In contrast, 3-(3,5-dichlorophenyl)-2,4-thiazo...

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Hlavní autoři: Frederick, Douglas M., Jacinto, Erina Y., Patel, Niti N., Rushmore, Thomas H., Tchao, Ruy, Harvison, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386561/
https://ncbi.nlm.nih.gov/pubmed/21964476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2011.09.015
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