Effect of gender, dose and time on 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT)-induced hepatotoxicity in Fischer 344 rats

1. The thiazolidinedione (TZD) ring present in drugs available for type II diabetes may contribute to hepatic injury. Another TZD ring-containing compound, 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT), produces liver damage in rats. Accordingly, the effects of gender, dose and time on DCPT he...

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Bibliografiska uppgifter
Huvudupphovsmän: Patel, Niti N., Crincoli, Christine M., Kennedy, Erica L., Frederick, Douglas M., Tchao, Ruy, Harvison, Peter J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922973/
https://ncbi.nlm.nih.gov/pubmed/18340566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498250701830267
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