ROLE OF LEUKOTRIENES IN N-(3,5-DICHLOROPHENYL)SUCCINIMIDE (NDPS) AND NDPS METABOLITE NEPHROTOXICITY IN MALE FISCHER 344 RATS

The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) can induce marked nephrotoxicity in rats following a single intraperitoneal (ip) administration of 0.4 mmol/kg or greater. Although NDPS induces direct renal proximal tubular toxicity, a role for renal vascular effects may also be p...

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Main Authors: Rankin, Gary O., Hong, Suk K., Anestis, Dianne K., Ball, John G., Valentovic, Monica A., Graffeo, Vincent A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412395/
https://ncbi.nlm.nih.gov/pubmed/22706168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2012.06.003
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