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Pattern, and not magnitude, of neural activity determines dendritic spine stability in awake mice

The stability of dendritic spines in the neocortex is profoundly influenced by sensory experience, which determines the magnitude and pattern of neural firing. By optically manipulating the temporal structure of neural activity in vivo using channelrhodopsin-2 and repeatedly imaging dendritic spines...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wyatt, Ryan M., Tring, Elaine, Trachtenberg, Joshua T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386353/
https://ncbi.nlm.nih.gov/pubmed/22706266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3134
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