Population imaging of neural activity in awake behaving mice

A longstanding goal in neuroscience has been to image membrane voltage across a population of individual neurons in an awake, behaving mammal. Here, we report a genetically encoded fluorescent voltage indicator, SomArchon, which exhibits millisecond response times and compatibility with optogenetic...

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Gepubliceerd in:Nature
Hoofdauteurs: Piatkevich, Kiryl D., Bensussen, Seth, Tseng, Hua-an, Shroff, Sanaya N., Lopez-Huerta, Violeta Gisselle, Park, Demian, Jung, Erica E., Shemesh, Or A., Straub, Christoph, Gritton, Howard J., Romano, Michael F., Costa, Emma, Sabatini, Bernardo L., Fu, Zhanyan, Boyden, Edward S., Han, Xue
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858559/
https://ncbi.nlm.nih.gov/pubmed/31597963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1641-1
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