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Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory

Modeling studies suggest that clustered structural plasticity of dendritic spines is an efficient mechanism of information storage in cortical circuits. However, why new clustered spines occur in specific locations and how their formation relates to learning and memory (L&M) remain unclear. Usin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Frank, Adam C., Huang, Shan, Zhou, Miou, Gdalyahu, Amos, Kastellakis, George, Silva, Tawnie K., Lu, Elaine, Wen, Ximiao, Poirazi, Panayiota, Trachtenberg, Joshua T., Silva, Alcino J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789055/
https://ncbi.nlm.nih.gov/pubmed/29379017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02751-2
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