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Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

Tau represents the subunit protein of one of the major hallmarks of Alzheimer disease (AD), the neurofibrillary tangles, and is therefore of major interest as an indicator of disease mechanisms. Many of the unusual properties of Tau can be explained by its nature as a natively unfolded protein. Exam...

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Detalles Bibliográficos
Main Authors: Mandelkow, Eva-Maria, Mandelkow, Eckhard
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385935/
https://ncbi.nlm.nih.gov/pubmed/22762014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a006247
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