Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers

Most anaplastic lymphoma kinase (ALK)–positive non–small cell lung cancers (NSCLCs) are highly responsive to treatment with ALK tyrosine kinase inhibitors (TKIs). However, patients with these cancers invariably relapse, typically within 1 year, because of the development of drug resistance. Herein,...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Katayama, Ryohei, Shaw, Alice T., Khan, Tahsin M., Mino-Kenudson, Mari, Solomon, Benjamin J., Halmos, Balazs, Jessop, Nicholas A., Wain, John C., Yeo, Alan Tien, Benes, Cyril, Drew, Lisa, Saeh, Jamal Carlos, Crosby, Katherine, Sequist, Lecia V., Iafrate, A. John, Engelman, Jeffrey A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385512/
https://ncbi.nlm.nih.gov/pubmed/22277784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003316
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