ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer

PURPOSE: Anaplastic lymphoma kinase (ALK) gene rearrangements define a distinct molecular subset of non–small cell lung cancer (NSCLC). Recently, several case reports and small series have reported that ALK rearrangements can overlap with other oncogenic drivers in NSCLC in crizotinib-naïve and criz...

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Detalhes bibliográficos
Main Authors: Gainor, Justin F., Varghese, Anna M., Ou, Sai-Hong Ignatius, Kabraji, Sheheryar, Awad, Mark M., Katayama, Ryohei, Pawlak, Amanda, Mino-Kenudson, Mari, Yeap, Beow Y., Riely, Gregory J., Iafrate, A. John, Arcila, Maria E., Ladanyi, Marc, Engelman, Jeffrey A., Dias-Santagata, Dora, Shaw, Alice T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874127/
https://ncbi.nlm.nih.gov/pubmed/23729361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0318
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