Impaired immune evasion in HIV through intracellular delays and multiple infection of cells

With its high mutation rate, HIV is capable of escape from recognition, suppression and/or killing by CD8(+) cytotoxic T lymphocytes (CTLs). The rate at which escape variants replace each other can give insights into the selective pressure imposed by single CTL clones. We investigate the effects of...

Full description

Saved in:
Bibliographic Details
Main Authors: Althaus, Christian L., De Boer, Rob J.
Format: Artigo
Language:Inglês
Published: The Royal Society 2012
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385478/
https://ncbi.nlm.nih.gov/pubmed/22492063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.0328
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items