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Impaired immune evasion in HIV through intracellular delays and multiple infection of cells

With its high mutation rate, HIV is capable of escape from recognition, suppression and/or killing by CD8(+) cytotoxic T lymphocytes (CTLs). The rate at which escape variants replace each other can give insights into the selective pressure imposed by single CTL clones. We investigate the effects of...

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Autors principals: Althaus, Christian L., De Boer, Rob J.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385478/
https://ncbi.nlm.nih.gov/pubmed/22492063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.0328
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