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Dynamics of Immune Escape during HIV/SIV Infection

Several studies have shown that cytotoxic T lymphocytes (CTLs) play an important role in controlling HIV/SIV infection. Notably, the observation of escape mutants suggests a selective pressure induced by the CTL response. However, it remains difficult to assess the definite role of the cellular immu...

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Detalhes bibliográficos
Main Authors: Althaus, Christian L., De Boer, Rob J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423483/
https://ncbi.nlm.nih.gov/pubmed/18636096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000103
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