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Prolongation of myocardial viability by proteasome inhibition during hypothermic organ preservation

Recently, we provided evidence for a possible role of the cardiac proteasome during ischemia, suggesting that a subset of 26S proteasomes is a cell-destructive protease, which is activated as the cellular energy supply declines. Although proteasome inhibition during cold ischemia (CI) reduced injury...

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Detalhes bibliográficos
Main Authors: Baker, Todd A., Geng, Qing, Romero, Jacqueline, Picken, Maria M., Gamelli, Richard L., Majetschak, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384525/
https://ncbi.nlm.nih.gov/pubmed/20875792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.09.093
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