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Proteasome inhibition prolongs survival during lethal hemorrhagic shock in rats

BACKGROUND: Several lines of evidence suggest that proteasomes, the major nonlysosomal proteases in eukaryotes, are involved in the pathophysiology of various disease processes, including ischemia-reperfusion injury and trauma. Recently, we demonstrated that 26S proteasome activity is negatively reg...

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Autors principals: Bach, Harold H., LaPorte, Heather M., Wong, Yee M., Gamelli, Richard L., Majetschak, Matthias
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182954/
https://ncbi.nlm.nih.gov/pubmed/23354244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e31827d5db2
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