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Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling

Six3 exerts multiple functions in the development of anterior neural tissue of vertebrate embryos. Whereas complete loss of Six3 function in the mouse results in failure of forebrain formation, its hypomorphic mutations in human and mouse can promote holoprosencephaly (HPE), a forebrain malformation...

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書誌詳細
主要な著者: Carlin, Dan, Sepich, Diane, Grover, Vandana K., Cooper, Michael K., Solnica-Krezel, Lilianna, Inbal, Adi
フォーマット: Artigo
言語:Inglês
出版事項: Company of Biologists 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383232/
https://ncbi.nlm.nih.gov/pubmed/22736245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.076018
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