Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling

Six3 exerts multiple functions in the development of anterior neural tissue of vertebrate embryos. Whereas complete loss of Six3 function in the mouse results in failure of forebrain formation, its hypomorphic mutations in human and mouse can promote holoprosencephaly (HPE), a forebrain malformation...

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Dettagli Bibliografici
Autori principali: Carlin, Dan, Sepich, Diane, Grover, Vandana K., Cooper, Michael K., Solnica-Krezel, Lilianna, Inbal, Adi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2012
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383232/
https://ncbi.nlm.nih.gov/pubmed/22736245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.076018
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