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Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling

Six3 exerts multiple functions in the development of anterior neural tissue of vertebrate embryos. Whereas complete loss of Six3 function in the mouse results in failure of forebrain formation, its hypomorphic mutations in human and mouse can promote holoprosencephaly (HPE), a forebrain malformation...

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Detalhes bibliográficos
Main Authors: Carlin, Dan, Sepich, Diane, Grover, Vandana K., Cooper, Michael K., Solnica-Krezel, Lilianna, Inbal, Adi
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383232/
https://ncbi.nlm.nih.gov/pubmed/22736245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.076018
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