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Identification, Isolation and Characterization of an Unknown Impurity of Varenicline

An unknown impurity formed during stability sample analysis by a gradient reversed phase ultra-high pressure liquid chromatography (UHPLC) of varenicline tablets at 0.2% level. A simple isocratic preparative method was developed to isolate the unknown impurity with 20 min run time. This unknown impu...

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Detalhes bibliográficos
Main Authors: Satheesh, Balasubramanian, Sree Ganesh, Kondayampettai K., Saravanan, Dhandayutham
Formato: Artigo
Idioma:Inglês
Publicado em: Österreichische Apotheker-Verlagsgesellschaft 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383220/
https://ncbi.nlm.nih.gov/pubmed/22896820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1201-08
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