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Isolation, Identification, and Characterization of an Unknown Impurity in Lovastatin EP
An unknown impurity in the fermentation-based drug substance lovastatin at 0.52 RRT was observed invariably in all batches when analyzed by HPLC as per the PhEur monograph. This impurity was isolated from the impurity-enriched sample using reversed-phase preparative HPLC and characterized by using s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Österreichische Apotheker-Verlagsgesellschaft
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951232/ https://ncbi.nlm.nih.gov/pubmed/24634841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1305-04 |
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