In Search of a Cytostatic Agent Derived from the Alkaloid Lycorine: Synthesis and Growth Inhibitory Properties of Lycorine Derivatives

As a continuation of our studies aimed at the development of a new cytostatic agent derived from an Amaryllidaceae alkaloid lycorine, we synthesized 32 analogues of this natural product. This set of synthetic analogues included compounds incorporating selective derivatization of the C1 versus C2 hyd...

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Detalhes bibliográficos
Main Authors: Evdokimov, Nikolai M., Lamoral-Theys, Delphine, Mathieu, Véronique, Andolfi, Anna, Frolova, Liliya V., Pelly, Stephen C., van Otterlo, Willem A. L., Magedov, Igor V., Kiss, Robert, Evidente, Antonio, Kornienko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383042/
https://ncbi.nlm.nih.gov/pubmed/22019045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.09.051
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