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Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a
Involution of the thymus results in reduced production of naive T cells, and this in turn is thought to contribute to impaired immunity in the elderly. Early T-cell progenitors (ETPs), the most immature intrathymic T-cell precursors, harvested from the involuted thymus exhibit a diminished prolifera...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382931/ https://ncbi.nlm.nih.gov/pubmed/22555975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-400002 |
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