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Causes, consequences, and reversal of immune system aging

The effects of aging on the immune system are manifest at multiple levels that include reduced production of B and T cells in bone marrow and thymus and diminished function of mature lymphocytes in secondary lymphoid tissues. As a result, elderly individuals do not respond to immune challenge as rob...

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Autores principales: Montecino-Rodriguez, Encarnacion, Berent-Maoz, Beata, Dorshkind, Kenneth
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582124/
https://ncbi.nlm.nih.gov/pubmed/23454758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64096
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