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Aging, B Lymphopoiesis, and Patterns of Leukemogenesis

The production of B lymphocytes begins to decline steadily early in adult life and is severely compromised in the elderly. This occurrence has been attributed to intrinsic defects in early hematopoietic progenitors and B cell precursors as well as to microenvironmental changes in aged bone marrow. T...

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Detalhes bibliográficos
Main Authors: Signer, Robert A.J., Montecino-Rodriguez, Encarnacion, Dorshkind, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924911/
https://ncbi.nlm.nih.gov/pubmed/17184948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.11.010
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