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Aldosterone-independent regulation of the epithelial Na(+) channel (ENaC) by vasopressin in adrenalectomized mice

The epithelial Na(+) channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) is under negative-feedback regulation by the renin–angiotensin–aldosterone system in protection of sodium balance and blood pressure. We test here whether aldosterone is necessary and sufficient for ENaC expressio...

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Detalhes bibliográficos
Main Authors: Mironova, Elena, Bugaj, Vladislav, Roos, Karl P., Kohan, Donald E., Stockand, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382497/
https://ncbi.nlm.nih.gov/pubmed/22665796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201978109
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